Lumbrokinase vs Nattokinase: Wane Sinadarin Fibrinolytic Ya Kamata Ku Zaɓa?

Yayin da yawan jama'a a duniya ke tsufa kuma yawan kamuwa da cututtukan zuciya da jijiyoyin jini ke ci gaba da ƙaruwa, ana ba da shi ta hanyar halitta, lafiya, kuma ta baki enzymes na fibrinolytic suna zama muhimmin yanki na ci gaba a masana'antar ƙarin abinci. Masu amfani da kayayyaki suna ƙara fifita samfuran halitta waɗanda suka dace da amfani na dogon lokaci tare da ƙarancin illa - ko dai a matsayin madadin ko kari ga magungunan hana zubar jini na gargajiya.

enzymes na fibrinolytic na baki, musamman lumbrokinase da nattokinasesuna ganin faɗaɗa buƙatar kasuwa saboda ingantattun hanyoyin da suka tsara don tallafawa zagayawar jini da lafiyar zuciya; sun shahara musamman a fannonin abinci da ƙarin lafiya masu amfani a Arewacin Amurka, Turai, da yankin Asiya-Pacific.

Lumbrokinase rukuni ne na enzymes na fibrinolytic da aka samo daga tsutsotsi na ƙasa, waɗanda suka ƙunshi isoenzymes guda shida na serine protease da ake samu a cikin nau'ikan halittu kamar Lumbricus rubellus da Pheretima aspergillum. Godiya ga ƙarfin aikin fibrinolytic da ikon hana tarin platelets, an tabbatar da cewa lumbrokinase yana da tasiri a asibiti wajen rigakafi da magance cututtukan zuciya da jijiyoyin jini.

Nattokinase ana samar da shi ta hanyar fermentation na waken soya marasa GMO ta amfani da Bacillus subtilis var. natto kuma an rarraba shi a matsayin sinadari mai suna serine protease guda ɗaya. A matsayin sinadari mafi aiki a cikin natto, nattokinase (NK) yana nuna ƙarfin aikin fibrinolytic tare da rage hawan jini, hana atherosclerosis, rage kitse, haɗakar platelet, da tasirin kariya daga jijiyoyi.

Tsarin thrombolytic na lumbrokinase yana da matuƙar takamaiman nau'in fibrin. Yana lalata fibrin mai alaƙa kai tsaye don ya narke cikin sauri toshewar jini; a lokaci guda, yana da aikin plasminogen activator (t-PA) na ciki, wanda ke ba shi damar kunna plasminogen na gida kai tsaye a wurin da aka samu gudan jini da kuma kauce wa matakai da yawa na biochemical.

Ba kamar magungunan thrombolytic na asibiti ba, lumbrokinase Ba ya canza plasminogen zuwa plasmin; saboda haka, ba ya haifar da hyperfibrinolysis na tsarin jiki kuma yana da ƙarancin haɗarin zubar jini. Bugu da ƙari, yana hana tarin platelets, yana nuna kwanciyar hankali mai zafi da alkaline, kuma ya dace da shan ta baki.

Nattokinase Yana amfani da wata hanya mai niyya da yawa don thrombolysis. Yana rage yawan sinadarin fibrin da plasmin kai tsaye don narke thrombi; a lokaci guda, yana canza prourokinase na sarkar guda ɗaya zuwa urokinase mai sarka biyu (uPA) kuma yana lalata plasminogen activator inhibitor-1 (PAI-1). Ta hanyar rage hana plasminogen activator nau'in nama (t-PA), yana ƙara matakan t-PA kuma yana haɓaka aikin fibrinolytic na ciki na jiki.

Ba kamar magungunan thrombolytic da aka saba amfani da su a asibiti kamar t-PA ba, nattokinase ba ya haifar da mummunan sakamako na zubar jini kuma ana iya ba shi ta baki.

Lumbrokinase Yawanci ana ƙididdige ayyukan da ake yi a cikin Raka'o'in Ƙasa da Ƙasa (IU) ko takamaiman raka'o'in aiki (U/mg). Duk da haka, rashin daidaitaccen ma'aunin ayyukan ƙasa da ƙasa, ƙarancin binciken allurar asibiti, da ƙarancin kwanciyar hankali na rukuni-zuwa-rukuni da ke tattare da yanayinsa a matsayin hadaddun enzymes masu yawa suna haifar da ƙalubale ga daidaitaccen sarrafa allurar da bin ƙa'idodi.

Nattokinase yana amfani da na'urorin FU da aka daidaita, kuma an tabbatar da ingancin maganinsa sosai (misali, 10,800 FU/rana don tasirin hana atherosclerosis). Yana nuna alaƙar amsawa da allurai da ingancin tsari mai daidaito, wanda ke sauƙaƙa samar da kayayyaki da ƙira mai yawa; ƙayyadaddun bayanai na kasuwanci galibi sun kama daga 5,000 FU/g zuwa 50,000 FU/g.

Idan aka kwatanta da lumbrokinase, nattokinase yana ba da fa'idodi masu mahimmanci na aminci. An tabbatar da shi ta hanyar nazarin toxicology mai bin ka'idar GLP kuma an nuna cewa ba ya canza yanayinsa, tare da ingantaccen tarihin amfani da ɗan adam wanda ya shafe shekaru da yawa a duniya. Bugu da ƙari, hanyoyin tsarkakewa na zamani suna ba da damar cire Vitamin K2 gaba ɗaya, ta haka yana kawar da tsangwama ga maganin hana ɗaukar ciki.

Da bambanci, lumbrokinase yana fitowa ne daga tushen dabbobi, yana ɗauke da haɗarin ƙazanta da yiwuwar rashin jin daɗin ciki; fa'idar da aka samu ta ka'idar "rashin kunna plasminogen" ba ta nuna wani bambanci mai mahimmanci ba a zahiri a aikace ta baki. Gabaɗaya, nattokinase yana ba da ƙarin bayanai masu ƙarfi game da aminci da kuma tsarin samarwa mai inganci, wanda hakan ya sa ya fi dacewa da kula da lafiya na dogon lokaci da bin ƙa'idodin fitarwa.

Dukansu biyun nattokinase da lumbrokinase Suna da yuwuwar illa ta ƙaruwar yawan zubar jini kuma suna da wasu dalilai da ba su dace ba don amfani da magungunan hana zubar jini kamar warfarin da aspirin; amfani da su a lokaci guda yana buƙatar kulawa sosai. Duk da haka, duka suna da kyakkyawan aminci ga hanta, ba tare da wata shaida ta ƙarin nauyin metabolism a kan hanta ko rahoton gubar hanta ba, wanda hakan ya sa suka dace da shan su na dogon lokaci ta baki.

Dukansu biyun nattokinase da lumbrokinase Ana iya shan su ta baki, suna da juriya ga acid, kuma suna shiga cikin hanji cikin tsari mai aiki. A asibiti, nattokinase yana mai da hankali kan lafiyar zuciya da jijiyoyin jini na yau da kullun da kuma rigakafin haɗarin thrombosis na dogon lokaci, yayin da ake amfani da lumbrokinase a matsayin magani mai dacewa ga yanayi kamar bugun kwakwalwa da cututtukan zuciya.

A ƙasashen duniya, foda natto nattokinase Ana rarraba shi sosai a matsayin ƙarin abinci a kasuwanni kamar Turai, Amurka, da Japan, tare da goyon bayan manyan tsare-tsare (misali, FDA GRAS, matsayin EU Novel Food); lumbrokinase yana samuwa a matsayin samfurin lafiya a Arewacin Amurka da Japan, kodayake hanyoyinsa na ƙa'ida suna da iyaka.

Kintainutri® ƙwararre ne a fannin bincike da haɓaka sinadarai da kuma samar da sinadarai masu tsafta na nattokinase. Kayayyakinmu sun haɗa da daga 5,000 zuwa 50,000 FU/g, yana da kyakkyawan daidaito a cikin rukuni, kuma ya cika takaddun shaida na ƙasashen duniya kamar ISO, GMP, Kosher, da Halal. Muna samar da ingantaccen tsarin samar da kayayyaki, cikakken tallafin fasaha, da kuma ayyukan OEM/ODM masu sassauƙa don taimakawa samfuran duniya ƙirƙirar samfuran lafiya na zuciya da jijiyoyin jini masu inganci, aminci, da kuma bin ƙa'idodi na kimiyya.

Namu foda natto nattokinase yana magance ƙalubalen da aka saba fuskanta a masana'antu, wato yawan sinadarin Vitamin K2 da ake samu a cikin ɗanyen natto, ta hanyar amfani da wani tsari na tsarkakewa mai zurfi don cire Vitamin K2 da kuma hana tsangwama ga zubar jini. Da fatan za a tuntuɓi Kintainutri® don neman tambayoyin sayayya.